![]() ![]() Additionally, ME were associated with nigrostriatal degeneration, according to DAT-SPECT. Patients with higher amounts of violent ME had a greater risk of phenoconversion therefore, their role as a predictor should be considered. Violent ME were associated with increased hazard ratio for phenoconversion in frequency (p = 0.012) and total duration (p = 0.007). 48401 Fremont BoulevardFremont, California 94538U.S.A.(510) 492-1088Fax: (510) 492-1098 Source for information on ESS Technology, Inc. During follow-up seven patients (24.1%) phenoconverted, yielding a yearly phenoconversion rate 8.3%. The ME frequency was negatively associated with tracer binding on dopamine transporter single-photon emission computed tomography (DAT-SPECT) the association was stronger for caudate nucleus compared to putamen. Of these ME, 68.4% were classified as minor/simple jerks, 9.3% as major, 21.7% as complex and 0.7% as violent. according to clinical severity: minor/simple jerks, major, complex and violent.Īn average frequency of 110.8 ± 75.2 ME per hour were identified in iRBD, 7.5 ± 11.6 in the controls (p < 0.001). ![]() The ME captured during REM sleep were classified into four categories, previously defined by Frauscher et al. and 33 controls (10 women, 23 men age 61.5 ± 8.2) were examined. Thirty-four iRBD patients (5 women, 29 men age 67.7 ± 7.2) with a mean follow-up duration 2.9 ± 1.1 years. The aim of this study was to perform a systematic visual analysis of the motor events (ME) captured during video-polysomnography, and clarify their relation to the disease severity. Abnormal motor manifestations in REM sleep are the most visible feature of idiopathic REM sleep behavior disorder (iRBD), which precedes the overt alpha-synucleinopathy. ![]()
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